Advanced Cell Biology

Overview

This module builds on the fundamental coverage of cell biology that is delivered in pre-requisite module BIO2104 (i.e. cell structure and function from the perspective of individual organelles, and their interactions, and how disease can arise when these break down).

In BIO2304 we focus on cutting edge techniques that can be used to investigate cell function at a variety of levels including:
Cell culture
Fluorescence microscopy
Transmission and scanning electron microscopy
RNAi / CRISPR
Proteomics
Inhibitors and drug development pipelines

We highlight how the use of these tools can provide a better understanding of disease mechanisms and aid the development of new treatment options. Case studies include:
Cancer cell biology
Stem cell research
Neurones and neurotransmitters

Learning Objectives

On successful completion of this module students will be able to:

LO1: Demonstrate an understanding of the theoretical basis of classical and emerging technologies that are used to study cells.
LO2: Appreciate how these tools can provide a deeper understanding of cell function and disease mechanisms.
LO3: Discuss how advances in technology is driving research into new therapeutic strategies for various diseases.
LO4: Appreciate the importance of experimental approach and apply practical cell biology methodologies.
LO5: Demonstrate scientific communication skills including report writing and peer discussion.
LO6: Demonstrate the ability to work as part of a team and reflect on their role in the team.
LO7: Appreciate health and safety in the laboratory and ethical practice.
LO8: Develop independent learning, critical thinking and problem solving ability.

Skills

Observation, recording, data analysis, microscopy, image analysis and experimental design. Practical skills in laboratory investigations including use of specialised software in data analysis, professional technical report writing and team-work.

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Assessment

Minimum exam mark 40%
Compulsory attendance at all practicals